Penetration of Clindamycin into Decubitus Ulcers

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Decubitus ulcers.

Decubitus ulcers are frequently encountered in the elderly and in bedridden or wheelchair-bound patients. Successful treatment is often difficult and expensive. Pressure, time, and friction are the major factors involved in the development of skin ulcers with such risk factors as age, female sex, and nutritional status predisposing to their development. Complications can be life threatening. A ...

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Penetration into bone and tissues of clindamycin phosphate.

Clindamycin phosphate is an antibiotic which is effective against both Staphylococcus aureus and the anaerobic organisms. In thirteen patients, its concentration following joint replacement was measured by the agar diffusion method. In bone, the concentration was (mean +/- s.e. mean) 5.01 microgram/ml +/- 1.16, N=10; in capsule, 3.29 microgram/ml +/- 0.71, N=12; measured between 1.75 and 3.75 h...

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Penetration into bone and tissues of clindamycin phosphate PETER BAIRD

Clindamycin phosphate is an antibiotic which is effective against both Staphylococcus aureus and the anaerobic organisms. In thirteen patients, its concentration following joint replacement was measured by the agar diffusion method. In bone, the concentration was (mean + s.e. mean) 5.01 pg/ml ± 1.16, N=10; in capsule, 3.29 pg/ml ± 0*71, N=12; measured between 1.75 and 3.75 hr after intramuscula...

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Decubitus ulcers: pathophysiology and primary prevention.

BACKGROUND Pressure sores are a serious complication of multimorbidity and lack of mobility. Decubitus ulcers have become rarer among bed-ridden patients because of the conscientious use of pressure-reducing measures and increased mobilization. Nonetheless, not all decubitus ulcers can be considered preventable or potentially curable, because poor circulation makes some patients more susceptibl...

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Decubitus ulcers: definitions, disagreements, and deductive etiology.

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1978

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.14.3.498